产品中心您现在的位置:首页 > 产品展示 > 抗体 > 内参抗体 > nVivoMAb anti-mouse IL-10

nVivoMAb anti-mouse IL-10

更新时间:2022-01-27

简要描述:

The JES5-2A5 monoclonal antibody reacts with mouse IL-10. IL-10 is a 17-21 kDa cytokine which is primarily produced by monocytes and, to a lesser extent, Th2 cells, mast cells, T regulatory cells, and

型号:厂商性质:代理商浏览量:73

The JES5-2A5 monoclonal antibody reacts with mouse IL-10. IL-10 is a 17-21 kDa cytokine which is primarily produced by monocytes and, to a lesser extent, Th2 cells, mast cells, T regulatory cells, and certain subsets of activated T and B cells. IL-10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggest that this cytokine is an essential immunoregulator in the intestinal tract. The JES5-2A5 antibody has been shown to neutralize the bioactivity of natural or recombinant IL-10.


产品名称:InVivoMab anti-mouse IL-10

反应种属:mouse

宿主来源:rat

实验应用:in vivo IL-10 neutralization, in vitro IL-10 neutralization

同种型:IgG1, κ

免疫原:Recombinant mouse IL-10

克隆性:Monoclonal

克隆号:JES5-2A5

产品浓度:Lot specific,typically between 4-11 mg/ml

保存温度:Undiluted at 4°C in the dark

运输温度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

预期分子量:150 kDa

产品形式:液体

有效期:One year from the date of receipt if stored as recommended

产地:美国


如需购买或咨询Bioxcell公司的产品,请联系Bioxcell金牌代理商欣博盛生物


留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
在线咨询
在线客服