更新时间:2022-01-27
The AFS98 monoclonal antibody reacts with mouse colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115. CSF1R is a single-pass ty
The AFS98 monoclonal antibody reacts with mouse colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115. CSF1R is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. In mice CSF1R is expressed by monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts. CSF1R is a receptor for CSF1 and CSF1 signaling through CSF1R regulates the proliferation and differentiation of cells in the monocytic lineage. The AFS98 antibody has been reported to deplete macrophages and block CSFR1 in vivo.
产品名称:InVivoMab anti-mouse CSF1R (CD115)
反应种属:mouse
宿主来源:rat
实验应用:in vivo macrophage depletion, in vitro CSF-R1 neutralization, in vivo monocyte depletion, Flow cytometry
同种型:IgG2a, κ
克隆性:Monoclonal
克隆号:AFS98
产品浓度:Lot specific,typically between 4-11 mg/ml
保存温度:Undiluted at 4°C in the dark
运输温度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit
预期分子量:150 kDa
产品形式:液体
有效期:One year from the date of receipt if stored as recommended
产地:美国
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