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6-keto-PGF1α ELISA kit产品介绍

更新时间:2024-02-19   点击次数:128次

高灵敏ELISA试剂盒,3小时内可检测低至1.40 pg/ml 6-酮前列腺素F1α

 

6-酮-前列环素F1α(6-keto-PGF1α)是前列环素(PGI2)的稳定水解产物。由于前列环素在缓冲液中的半衰期很短(2-3分钟),通常通过测量尿液中的6-酮-前列环素F1α代谢物及其衍生物2,3-二酮-前列环素F1α来监测前列环素的产生。前列环素具有自分泌功能,包括抑制血小板聚集、抑制加压激素导致的血管收缩反应、血小板解聚等特性以及生殖功能。这些效应是由受体介导的cAMP的升高所引起的。前列腺素在动脉粥样硬化和保护心肌缺血方面有临床应用。

Enzo Life Sciences/欣博盛生物 的6-酮-前列环素F1α比色法ELISA试剂盒,可在3小时内得到检测结果,在405nm处读取OD值。该试剂盒特异性高,与结构相关的分子交叉反应性低。6-酮-前列环素F1α ELISA试剂盒已经在各种类型样品中得到了充分验证。欣博盛生物作为Enzo life sciences授权中国一级代理,可提供该产品,欢迎咨询。

 

产品特点

◆ 三小时内可快速得到38份样品(带复孔)的实验结果

◆ 高特异性,与结构相关分子交叉反应性低

◆ 已使用各种样品进行了充分验证,可靠性高

◆ 广泛的文献引用

 

产品信息

产品货号

ADI-900-004/ ADI-901-004

产品名称

6-keto-PGF1α ELISA kit(6-酮前列腺素F1α ELISA试剂盒)/欣博盛生物

规格

96 wells/ 5x96 wells

其他名称

6-keto Prostaglandin F1α

灵敏度

1.40 pg/ml

检测范围

3.2 - 50,000 pg/ml

应用

ELISA, Colorimetric detection

适用样本类型

细胞培养上清,血清,唾液和尿液

检测波长

405 nm

适用种属

不限种属

运输

Blue Ice Not Frozen

长期保存

+4°C

试剂盒组分

DxS IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, 

Standard, pNpp Substrate, Stop solution

 

标准曲线示例

6-keto-PGF1α ELISA kit——ENZO热销产品 

 

部分产品引用文献

1. Laser Speckle Contrast Imaging-based diagnosis of severe mesenteric traction syndrome: Hemodynamics and prostacyclin - A prospective cohort study: A.A. Olsen, et al.; Microvasc. Res. 147, 104505 (2023)

2. Contribution of cyclooxygenase-1-dependent prostacyclin synthesis to bradykinin-induced dermal extravasation: M. Krybus, et al.; Biomed. Pharmacother. 148, 112786 (2022)

3. Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage: K.M. Mirabito Colafella, et al.; Clin. Sci. (Lond.) 136, 675 (2022)

4. Estrogen modulates metabolic risk profile after resistance training in early postmenopausal women: a randomized controlled trial: T.V. Dam, et al.; Menopause 28, 1214 (2021)

5. Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2: S. Lucotti, et al.; J. Clin. Invest. 129, 1845 (2019)

6. Evidence for increased content of PGF2α, PGE2 and 6-keto-PGF1α in endometrial tissue cultures from heavy draft mares in anestrus with endometritis: M.J. Siemieniuch, et al.; J. Equine Vet. Sci. 77, 107 (2019)

7. Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation: E. Buczek, et al.; BMC Cancer 18, 582 (2018)

8. Inhibitory Effects of an Orally Active Thromboxane A2 Receptor Antagonist, nstpbp5185, on Atherosclerosis in ApoE-Deficient Mice: S.W. Huang, et al.; Thromb. Haemost. 118, 401 (2018)

9. Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis: M.J. Siemieniuch, et al.; Theriogenology 103, 191 (2017), Application(s): ELISA using culture supernatants

10. Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor: Z. Drebert, et al.; Vascul. Pharmacol. 89, 19 (2017), Application(s): Determine the concentrations of prostanoids in conditioned medium from myofibroblasts and HUVECs, and in HUVEC lysates

 

 

6-keto-PGF1α ELISA kit——ENZO热销产品

详情请联系ENZO 金牌代理商-欣博盛生物科技