InVivoMab anti-mouse PD-1 (CD279)抗体

Programmed death-1 (PD-1)是在T细胞上表达的抑制性受体，它能促进炎性T细胞的凋亡并抑制抗炎调节性T细胞的凋亡，从而提高自身耐受性并预防自身免疫性疾病。为了逃避免疫监视，肿瘤细胞经常通过过度表达PD-L1来利用这一系统，PD-L1是一种结合并激活PD-1的配体。抗PD-1单克隆抗体用于阻断PD-L1与PD-1的结合，从而使免疫系统能够发现并杀死肿瘤细胞。

产品名称:InVivoMab anti-mouse PD-1 (CD279)抗体

反应种属:mouse

宿主来源:rat

实验应用:in vivo blocking of PD-1/PD-L signaling

同种型:IgG2a, κ

免疫原:Syrian Hamster BKH cells transfected with mouse PD-1 cDNA

克隆性:Monoclonal

克隆号:RMP1-14

产品浓度:Lot specific,typically between 4-11 mg/ml

保存温度:Undiluted at 4°C in the dark

运输温度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

预期分子量:150 kDa

产品形式:液体

有效期:One year from the date of receipt if stored as recommended

产地:美国

InVivoMab anti-mouse PD-1 (CD279)抗体

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