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Ganglioside GQ1b . tetrasodium salt (bovine brain)

更新时间:2022-01-28

简要描述:

Ganglioside GQ1b . tetrasodium salt (bovine brain)
Specifically promotes neural differentiation of human neuroblastoma cells.

型号:厂商性质:代理商浏览量:116

Ganglioside GQ1b . tetrasodium salt (bovine brain)   

Product Details

Alternative Name:GQ1b . 4Na (bovine brain), Tetrasialoganglioside GQ1b . 4Na (bovine brain)

Sequence:[II3(Neu5Ac)2, IV3(Neu5Ac)2GgOse4Cer] [[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-Gal(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1→1’)-Cer]

Formula:C106H178N6O55 . 4Na

MW:2416.6 . 92.0 (calculated on sphingosine C18:1 and stearic acid)

CAS:68652-37-9

Purity:≥98% (TLC)

Appearance:Lyophilized.

Solubility:Soluble in water, biological buffers or DMSO.

Shipping:Ambient

Long Term Storage:-20°C

Use/Stability:If stored at -20°C the product is stable for at least 2 years. After reconstitution the solution should be stored at -20°C and is stable for at least 1 year.

Regulatory Status:RUO - Research Use Only

ALX-302-012
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ALX-302-012


Product Literature References

Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer’s disease mouse model, and causes reduction of amyloid precursor protein: M.K. Shin, et al.; Sci. Rep. 9, 8512 (2019), Abstract; Full Text
GQ1b, a bioactive ganglioside that exhibits novel nerve growth factor (NGF)-like activities in the two neuroblastoma cell lines: S. Tsuji, et al.; J. Biochem. 94, 303 (1983), Abstract;


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