更新时间:2022-01-28
α2-Macroglobulin (human plasma), (purified)品牌: ENZO产品货号: BML-SE502-0001规格: 1*1mg如需购买该产品或咨询其他问题,请联系ENZO一级代理商-欣博盛生物
α2-Macroglobulin (human plasma), (purified)
MW: | 725 kDa |
Source: | Isolated from human plasma that is tested to be negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2. |
UniProt ID: | P01023 |
Shipping: | Shipped on Blue Ice |
Long Term Storage: | -20°C |
Scientific Background: | In addition to binding TGF-β and β-amyloid, α2-macroglobulin covalently binds and inhibits a wide range of proteases, including ADAMs, calpains, cathepsins, chymase, clotting factors, kallikreins, MMPs, neutrophil elastase, and proteinase 3. It also plays a role in the innate immune system, inhibiting parasitic proteases. When treated with methylamine, it blocks binding of apoE to lipoprotein receptor-related protein (LRP). |
Regulatory Status: | RUO - Research Use Only |