更新时间:2022-03-02
CleanCap® Reagent AG (3' OMe) is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up…
CleanCap® Reagent AG (3' OMe) is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency1.
CleanCap AG (3' OMe) includes the 5' N7-Methyl-3'-O-Methylguanosine commonly found in mRNA capped using ARCA, whereas CleanCap AG (N-7113) has a naturally occurring 5' N7-Methylguanosine structure.
Catalog No | N-7413 |
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Purity | ≥95% by AX-HPLC |
Extinction Coefficient | 30,539 Lmol-1cm-1 at 255 nm |
Molecular Formula | C33H45N15O24P4 (free acid) |
Molecular Weight | 1159.60 |
Salt Form | Na+ |
Concentration | 100 mM |
Buffer | H2O |
Recommended Storage | -20°C or below |
Other Name(s) | CleanCap®Reagent AG (3' OMe) for co-transcriptional capping of mRNA, m7(3'OMeG)(5')ppp(5')(2'OMeA)pG |
Application | CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases |
Backbone | 5'-5'-Triphosphate |
Base Analog(s) | Adenosine, Guanosine |
Nucleotide Category | Cap analogs |