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N1-Methylpseudouridine-5'-Triphosphate - (N-1081)

更新时间:2022-03-02

简要描述:

N1-Methyl-Pseudouridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity …

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Description

N1-Methyl-Pseudouridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.

Product Details

Catalog NoN-1081
Purity≥90% by AX-HPLC
Extinction Coefficient8,877 Lmol-1cm-1 at 271 nm
Molecular FormulaC10H17N2O15P3 (free acid)
Molecular Weight498.10 g/mole (free acid)
Salt FormLi+
Concentration100 mM
BufferH2O
Recommended Storage-20°C or below
Other Name(s)N1-Methylpseudo-UTP, 1-Methylpseudo-UTP
ApplicationAptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone5'-Triphosphate
Base Analog(s)Pseudouridine
Sugar Type(s)RNA
Nucleotide CategoryBase Modified RNA


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