Ionomycin (SIH-228)的化学结构图, Ca2+ 离子载体. CAS #: 56092-81-0. 分子式: C41H70O9. 分子量: 709.01 g/mol.
产品详情
产品名称:Ionomycin
产品描述:Ca2+ 离子载体
纯度:>98%
CAS号:56092-81-0
分子式:C41H70O9
分子量:709.01
储存温度:-20ºC
运输温度:常温运输
产品类型:诱导剂
溶解性:在乙醇中溶解度是10mM, DMSO中是10mM
来源:合成的
性状:无色固体
SMILES:C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)O
InChI:InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23
InChIKey:PGHMRUGBZOYCAA-OJFQOPKISA-N
安全术语:安全级别: 注意: 物质尚未充分测试. 安全术语: S22 -不要吸入粉尘 S24/25 - 避免皮肤和眼睛接触 S36/37/39 - 穿戴适当的防护服、手套和眼睛/面部保护 危险术语: H302, 吞食有害
引用该产品:Ionomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-228)
别名:Ionomycin, Ionomycin calcium salt
研究领域:癌症, 细胞凋亡
PubChem ID:6434517
科研背景:Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187.
参考资料:1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495.
2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112.
产品文献:
Isolation and immunophenotyping by flow cytometry of canine peripheral blood and intraepithelial and lamina propria duodenal T lymphocytes.
Agulla, B. et al. (2021) Vet. Immunol. Immunopathol. . 239:110305
PubMed ID: 34352607 应用范围: In vitro stimulation
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