技术文章您现在的位置:首页 > 技术文章 > Rat Leptin (瘦素) ELISA kit--ENZO热销产品

Rat Leptin (瘦素) ELISA kit--ENZO热销产品

更新时间:2023-06-09   点击次数:245次

瘦素(Leptin)是由ob基因编码、在脂肪组织中生成的一种脂肪代谢调控产物,在代谢和调控体重等方面发挥重要作用。它通过下丘脑中的瘦素受体发出信号,降低食欲,增加能量消耗。在外周组织中,瘦素能拮抗胰岛素信号传导,增加脂肪酸氧化,减少胰岛β细胞的胰岛素分泌,并促进生育。它在脂肪细胞中的表达可以被其他脂肪因子如IL-6(刺激)和TNF-α(抑制)以旁分泌方式调节。瘦素缺乏的小鼠表现出严重的胰岛素抵抗、肥胖和生育能力下降,所有这些都可以通过外源性瘦素给药而逆转。

 

 无边缘效应:所有孵育步骤在常温下进行消除了37°C下蒸发的风险

 检测范围广:易于定量检测高水平和低水平瘦素

● 方便:所有试剂保存在4°C

● 快速:仅需3小时就可获得39个样本的重复结果

 预包被板和即用型试剂为您节省实验时间

 

ENZO热销产品——Leptin (rat), ELISA kit

 

产品信息

产品货号

ADI-900-015A

产品名称

Leptin (rat), ELISA kit(大鼠瘦素ELISA试剂盒)

规格

96 wells

灵敏度

67.2 pg/ml

检测范围

100- 6,400 pg/ml

检测时间

3 hours

样本种属

Rat

样本类型

culture supernatants, plasma, and serum

保存温度

+4°C

试剂盒组分

Microtiter plate, Standard, Antibody, Conjugate, Assay buffer 28, TMB Substrate, Stop solution 2, Wash buffer concentrate


部分产品引用文献

1. Altered motor, anxiety-related and attentional task performance at baseline associate with multiple gene copies of the vesicular acetylcholine transporter and related protein overexpression in ChAT::Cre+ rats: C.P. Mantanona, et al.; Brain Struct. Funct. 224, 3095 (2019) 

2. Long-term feeding of red algae (Gelidium amansii) ameliorates glucose and lipid metabolism in a high fructose diet-impaired glucose tolerance rat model: H.C. Liu, et al.; J. Food Drug Anal. 25, 543 (2017), Application(s): Determination of leptin, rat plasma 

3. Melatonin supplementation plus exercise behavior ameliorate insulin resistance, hypertension and fatigue in a rat model of type 2 diabetes mellitus: M.M. Rahman, et al.; Biomed. Pharmacother. 92, 606 (2017) 

4. Effect of Intermittent Hypoxia on Arcuate Nucleus in the Leptin-Deficient Rat: J. Ciriello, et al.; Neurosci. Lett. 626, 112 (2016), Application(s): Measured leptin levels in rat aqueous plasma phase 

5. Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats: A. Malta, et al.; Sci. Rep. 6, 30745 (2016), Application(s): Leptin level quantification 

6. Impact of prenatal exposure to obesogenic environment on later-life brown and white adipocytes and liver outcomes: L. Bezpalko, et al.; Proc. Shevchenko Sci. Soc. Medicine 41, 33 (2015), Application(s): ELISA using rat serum 

7. Lactobionic acid reduces body weight gain in diet-induced obese rats by targeted inhibition of galectin-1: R. Mukherjee, et al.; Biochem. Biophys. Res. Commun. 463, 1311 (2015), Application(s): ELISA using rat plasma



ENZO热销产品——Dopamine(多巴胺)ELISA kit

更多详情请联系Enzo Life Sciences授权全国代理商-欣博盛生物