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Plasmocure™

更新时间:2022-01-28

简要描述:

Plasmocure™ is a second-line anti-mycoplasma reagent. It is recommended for the elimination of mycoplasma that appear to be Plasmocin™ -resistant [1].Plasmocure™ combines two antibiotics that act ……

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Alternative mycoplasma removal reagent for cell cultures


Plasmocure™ is a second-line anti-mycoplasma reagent. It is recommended for the elimination of mycoplasma that appear to be Plasmocin™ -resistant [1].


Plasmocure™ combines two antibiotics that act through different mechanisms than those found in Plasmocin™:

– the first antibiotic binds to the 50S subunit of the ribosome and blocks peptidyltransferase activity

– the second antibiotic binds to isoleucyl-tRNA synthetase and halts isoleucine incorporation into mycoplasma proteins.


A two-week treatment with Plasmocure™ is usually sufficient to completely eliminate mycoplasma. If mycoplasma elimination is not completed after two weeks, Plasmocure™ can be administered for an additional week. A moderate slowdown of cell growth may be observed, but full recovery of the cell line is expected once mycoplasma are eliminated.

One 1 ml vial is sufficient to treat 1 to 3.3 liters of culture.


Important: InvivoGen's anti-mycoplasma products are suitable for research purposes only, and not for human or animal care.


Specifications

Product concentration: 100 mg/ml


Elimination of mycoplasmas in two weeks (recommended concentration of 50 μg/ml)


Endotoxin level: < 0.5 EU/mg


Physicochemical characterization: pH and appearance


Cell culture tested: potency validated on bacterial reference strains


Contents

Plasmocure™ is provided as a cell culture tested, sterile filtered solution at a concentration of 100 mg/ml.


 Plasmocure™ is shipped a t room temperature


 Upon receipt it can be stored at 4°C for 12 months or at -20°C for long-term storage.


如需购买或咨询该产品技术问题,请联系Invivogen一级代理商-欣博盛生物


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