CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs) [1].These CpG motifs are present at a 20-fold greater frequency in ……

Pam3CSK4 (Pam3CysSerLys4) is a synthetic triacylated lipopeptide (LP) and a TLR2/TLR1 ligand. It is a potent activator of the pro-inflammatory transcription factor NF-κB [1, 2]. Pam3CSK4 mimics the ……

Phorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a specific activator of Protein Kinase C (PKC) and hence activates nuclear factor-kappa B (NF-κB)……

Poly(dA:dT) is a poly(deoxyadenylic-deoxythymidylic) acid sodium salt. It is a repetitive synthetic double-stranded DNA sequence of poly(dA-dT):poly(dT-dA) and a synthetic analog of B-DNA.

Poly(dA:dT) is a poly(deoxyadenylic-deoxythymidylic) acid sodium salt. It is a repetitive synthetic double-stranded DNA sequence of poly(dA-dT):poly(dT-dA) and a synthetic analog of B-DNA.Poly…

Poly(dG:dC) is a poly(deoxyguanylic-deoxycytidylic) acid sodium salt. It is a repetitive synthetic double-stranded DNA sequence of poly(dG-dC)•poly(dC-dG). Intracellular poly(dG:dC) is detected by se…

Polyinosinic-polycytidylic acid (i.e. poly(I:C)) is a synthetic analog of double-stranded RNA (dsRNA), a molecular pattern associated with viral infection. InvivoGen’s Poly(I:C) LMW (Low Molecular ……

TLR7/8 Agonist - Imidazoquinoline compound R848 (Resiquimod) is an imidazoquinoline compound with potent anti-viral activity. This low molecular weight synthetic molecule activates immune cells via ……

TLR8 Agonist - HIV-1 LTR-derived ssRNA / LyoVec™ ssRNA40 is a 20-mer phosphorothioate protected single-stranded RNA oligonucleotide containing a GU-rich sequence.ssRNA40, also known as R-1075, is a ……